3-AMINOPIPERIDINE PIPERIDIN-3-YLAMINE

Name	3-aminopiperidine dihydrochloride
Synonyms	piperidin-3-amine 3-AMINOPIPERIDINEHCL 3-AMINOPIPERIDINEDIHCL 3-AMINOPIPERIDINE 2HCL 3-aminopiperidine hydrochloride piperidin-3-amine dihydrochloride 3-AMINOPIPERIDINE DIHYDROCHLORIDE 3-aminopiperidine dihydrochloride 3-Amino piptrdine dihydro chloride 3-AMINOPIPERIDINE PIPERIDIN-3-YLAMINE (3R)-piperidin-3-amine dihydrochloride
CAS	138060-07-8
EINECS	630-778-2
InChI	InChI=1/C5H12N2.2ClH/c6-5-2-1-3-7-4-5;;/h5,7H,1-4,6H2;2*1H/t5-;;/m1../s1

Molecular Formula	C5H14Cl2N2
Molar Mass	173.08
Melting Point	230°C (dec.)(lit.)
Boling Point	241.9°C at 760 mmHg
Flash Point	100.1°C
Water Solubility	Partly miscible in water.
Solubility	Methanol (Sparingly), Water (Slightly)
Vapor Presure	0.028mmHg at 25°C
Appearance	White to light yellow solid
Color	Off-white to beige
Storage Condition	Inert atmosphere,Room Temperature
Sensitive	Hygroscopic
MDL	MFCD00012773
Physical and Chemical Properties	Melting point 230°C (dec.)
Use	This product is for scientific research only and shall not be used for other purposes.

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection S36 - Wear suitable protective clothing.
WGK Germany	3
HS Code	29333990
Hazard Note	Irritant

overview	3-aminoperidine hydrochloride is a key chiral intermediate for the synthesis of liragliptin and alogliptin for the treatment of type II diabetes.
use	3-aminopiperidine dihydrochloride is a white to white crystal, which is a key intermediate of two new diabetic drugs alogliptin and liptin, and is also a fine chemical intermediate of other pesticides and additives.
preparation	ethyl 3-piperidinoate is used as the starting material, after D-tartaric acid: resolution, multiple crystallization, dissociation, and the upper benzyl group to prepare (R)N-benzyl -3-piperidinoate ethyl ester, the ester is hydrolyzed to produce acid, and the acid reacts with diphenyl azide phosphate, and rearrangements occur at the same time, (R)-1-N-benzyl-3-N-tert-butoxycarbonyl-aminopiperidine was prepared, and then (R)-3-aminopiperidine dihydrochloride was prepared after debenzylation and debutoxycarbonylation and salt formation.

Last Update：2024-04-09 02:00:06

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Product Name: 3-Aminopiperidine dihydrochloride Visit Supplier Webpage Request for quotation
CAS: 138060-07-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

Product Name: 3-Aminopiperidine dihydrochloride Request for quotation
CAS: 138060-07-8
Tel: 0086-13605431940
Email: xuli678323@126.com
Mobile: +86-13605431940
QQ: 56860987

Wechat: 13605431940
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3-AMINOPIPERIDINE PIPERIDIN-3-YLAMINE

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